CD3 (Cy5)
Catalogue Number: C2254-56Q-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with Cy5. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests |
| Host name: | Mouse |
| Clone: | 5K205 (UCHT1) |
| Isotype: | IgG1, kappa |
| Immunogen: | Human thymocytes and peripheral blood lymphocytes from a patient with Sezary cell leukemia. |
| Application: | FC |
Description
Description: CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28kD and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation.
Additional Text
Caution
FOR RESEARCH USE ONLY
Specificity
Recognizes the 20kD epsilon chain of the CD3/T cell antigen receptor complex.
Purification
Purified
Antibody Clonality
Monoclonal
C2254-56Q Datasheet
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