CD5 (T-cell Surface Glycoprotein CD5, Lymphocyte Antigen T1/Leu-1, LEU1) (MaxLight 490)
Catalogue Number: C2255-85P-ML490-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | UCHT2 |
| Isotype: | IgG1 |
| Immunogen: | Thymocytes and Sezary T cells |
| Application: | FC, IP, WB, IHC |
Description
Description: MaxLight™ 490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins.
Additional Text
Purification
Purified
Antibody Clonality
Monoclonal
C2255-85P-ML490 Datasheet
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