CD5 (CD5 Antigen, CD5 Molecule, LEU1, Lymphocyte Antigen CD5, Lymphocyte Antigen T1/Leu 1, Lymphocyte Glycoprotein T1/Leu1, p56 62, T cell Surface Glycoprotein CD5, T1) (MaxLight 490)
Catalogue Number: C2256-12M-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rat |
| Clone: | 10B1757 (YKIX322.3) |
| Isotype: | IgG2a |
| Immunogen: | Concanavilin A activated canine peripheral blood cells |
| Application: | FC, IP, IHC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. CD5, a 67kD cell surface type 1 transmembrane glycoprotein also known as Lymphocyte antigen T1, Ly-1 or Leu-1. CD5 is expressed on the surface of T cells and thymocytes, CD5 is also expressed by NK cells at low levels (Huang et al. 2008). CD5 was clustered as canine CD5 in the First Canine Leucocyte Antigen Workshop (Cobbold et al. 1994). In a study of 73 cases of canine chronic lymphocytic leukemia (CLL) CD5 expression was absent on all cases of B cell CLL as defined by CD21 expression and lack of CD3 or other T cell antigen expression (Vernau and Moore 1999). CD5 serves as a useful marker for the discrimination of canine leukemias of differing origins (Villiers 2002).
Additional Text
Specificity
Recognizes canine CD5.
Purification
Protein G purified
Antibody Clonality
Monoclonal
C2256-12M-ML490 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations