CD11a (Leukocyte Function Associated Antigen, LFA-1, Integrin aL) (PE/Cy7)
Catalogue Number: C2262-27F-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, 0.09% sodium azide, and a stabilizing agent. Labeled with PE/Cy7. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | 5K221 (I21/7) |
| Isotype: | IgG2a, kappa |
| Immunogen: | CD11a |
| Application: | FC, IP, WB, IHC |
Description
Description: Leukocyte Function-associated Antigen-1 (LFA-1) is a member of the integrin family of cell adhesion molecules (1, 2). The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow (2). CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Co-stimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1 (1, 2).
Additional Text
Caution
FOR RESEARCH USE ONLY
Specificity
Recognizes the alpha subunit of mouse of LFA-1 at 180kD.
Purification
Purified
Antibody Clonality
Monoclonal
C2262-27F Datasheet
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