CD11b (Cell Surface Glycoprotein MAC1 Alpha Subunit, Complement Component Receptor 3 Alpha, CR3A, ITGAM, MAC1A, MO1A, Neutrophil Adherence Receptor) (MaxLight 490)
Catalogue Number: C2262-36R-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | ICRF44 |
| Isotype: | IgG1 |
| Immunogen: | Rheumatoid synovial cells and human monocytes. |
| Application: | IP, IHC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. CD11b cell surface glycoprotein is a 165kD molecule also known as the alphaM integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes.
Additional Text
Gene Name
ITGAM
Gene ID
3684
Uniprot ID
P11215
Specificity
Recognizes human CD11b. Species Crossreactivity: Cynomolgus monkey, baboon, Rhesus monkey. Does not react with feline. Rreported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release
Purification
Protein G purified
Antibody Clonality
Monoclonal
C2262-36R-ML490 Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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