CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor) (MaxLight 550)
Catalogue Number: C2262-40J-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rat |
| Clone: | 3H977 (M1/70.15) |
| Isotype: | IgG2b |
| Immunogen: | T cell enriched splenocytes from B10 mice. |
| Application: | FC, IP, IHC |
Additional Text
Specificity
Recognizes the mouse CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone 3H955.15 has been reported to block iC3b binding to its receptor (3).* Has been reported to as being suitable for use on plp fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue (4.
Purification
Protein G purified
Uniprot ID
P05555
Antibody Clonality
Monoclonal
C2262-40J-ML550 Datasheet
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