CD11c (Monocyte/Macrophage, CD11 Antigen-like Family Member C, Complement Component 3 Receptor 4 Subunit, Integrin alphaX, ITGAX, ITAX, Leukocyte Adhesion Glycoprotein p150,95 alpha Chain, Leukocyte Adhesion Receptor p150,95, Leu M5, Leukocyte Surface Ant
Catalogue Number: C2262-56U-ML550-USB
| Manufacturer: | United States Biological |
| Preservative: | Azide-free |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | CBR-p150/4G1 |
| Isotype: | IgG2a |
| Immunogen: | Recombinant protein corresponding to human CD11c. |
| Application: | FC, IHC |
Description
Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. Human CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150, is a ~150kD type I transmembrane protein and member of the integrin alpha chain family expressed by monocytes and macrophages, granulocytes and NK cells. CD11c is a marker fo hairy cell leukemia cells. CD11c combines with CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, and acts as a mediator of leukocyte adherence to the endothelium. CD11c also binds to the ligands CD54 (ICAM1), iC3b ,and fibrinogen.
Additional Text
Specificity
Recognizes human CD11c. Does not recognize CD11a, CD11b or CD18.
Purification
Protein A purified
Antibody Clonality
Monoclonal
Full Name
CD11c (Monocyte/Macrophage, CD11 Antigen-like Family Member C, Complement Component 3 Receptor 4 Subunit, Integrin alphaX, ITGAX, ITAX, Leukocyte Adhesion Glycoprotein p150,95 alpha Chain, Leukocyte Adhesion Receptor p150,95, Leu M5, Leukocyte Surface Antigen p150,95 alpha Subunit, Myeloid Membrane Antigen alpha Subunit, p150,95 Integrin alpha Chain) (Azide Free) (MaxLight 550)
C2262-56U-ML550 Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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