CD16 (Fc gamma RIII alpha, NK cells) (MaxLight 650)
Catalogue Number: C2267-30L-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 10B814 (DJ130c) |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IHC |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. CD16 is a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. DJ130c recognises all polymorphonuclear cells irrespective on their NA phenotype.
Additional Text
Specificity
Recognizes human CD16. Recognizes an epitope in the first membrane-distal domain of CD16 and reacts with both CD16a and CD16b. Crossreacts with CD16 from rhesus macaques, Macaca mulatta.
Purification
Protein G purified
Antibody Clonality
Monoclonal
C2267-30L-ML650 Datasheet
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