CD19 (Carboxyfluorescein)
Catalogue Number: C2269-83N2-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with Carboxyfluorescein. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests |
| Host name: | Mouse |
| Clone: | 8H213 (4G7-2E3) |
| Isotype: | IgG1 |
| Immunogen: | Human chronic lymphocytic leukemia cells |
| Application: | FC |
Description
Description: CD19 is a 95kD transmembrane glycoprotein with two Ig-like C2-set domains. CD19 regulates B cell development and activation through interactions with CD21, CD22, and the B cell receptor. CD19 polymorphisms and upregulation lead to the development of autoimmunity by promoting autoantibody production. Within the extracellular domain, human CD19 shares 57% aa sequence identity with mouse and rat CD19.
Additional Text
Caution
FOR RESEARCH USE ONLY
Specificity
Recognizes human CD19.
Purification
Protein G purified
Antibody Clonality
Monoclonal
C2269-83N2 Datasheet
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