CD24 (GPI-linked surface Mucin, Nectadrin, Heat stable antigen, HSA) (PE/CY5)
Catalogue Number: C2275-05E-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, 0.09% sodium azide and a stabilizing agent. Labeled with PE/CY5. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | 5K10 (91) |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC, IP, IHC |
Description
Description: CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes.1-3 The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes.4-6 Its ligand is P-selectin (CD62P).7 CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes.1-3 Can be used to inhibit B-cell differentiation.
Additional Text
Caution
FOR RESEARCH USE ONLY
Gene ID
12484
Specificity
Recognizes mouse CD24; Mr 95kD.
Purification
Purified
Uniprot ID
P24807
Gene Name
Cd24a
Antibody Clonality
Monoclonal
C2275-05E Datasheet
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