Anti-Mouse CD122 (IL-2Rβ) - Biotin

Catalogue Number: C2327-LET

Manufacturer:Leinco Technologies, Inc
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 50 ug, 500 ug
Host name:
Clone: TM-β1
Isotype:
Immunogen:

Description

Description: CD122 is a 70-75 kD IL-2 receptor β chain that is a type I membrane protein. CD122 is involved in T cell-mediated immune responses and its activation increases proliferation of CD8+ effector T cells. It exists in three forms with varying degrees of binding affinity with IL-2. The low affinity form is a monomer of the α subunit and has no involvement in signal transduction. The intermediate affinity form is a γ/β heterodimer and the high affinity form is an α/β/γ heterotrimer. The intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. This protein also interacts with the IL-15 receptor.

Additional Text

Concentration

0.5 mg/ml

Antibody Clonality

Monoclonal

Storage Note

This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.