CD28 (CD28 Antigen, CD28 Molecule, T cell Antigen CD28, T cell Specific Surface Glycoprotein, T cell Specific Surface Glycoprotein CD28, Tp44) (MaxLight 490)

Catalogue Number: C2380-01J1-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rat
Clone: 6A266 (YTH913.12)
Isotype: IgG2b
Immunogen: Human peripheral blood T-cells
Application: FC, IHC

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. CD28 is a t ype of I disulfide-linked homodimer that is expressed on most thymocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many but not all T cell independent immune responses.

Additional Text

Specificity

Recognizes human CD28.

Purification

Protein G purified

Antibody Clonality

Monoclonal