CD28 (Biotin)
Catalogue Number: C2380-08J-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with Biotin. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ug |
| Host name: | Hamster |
| Clone: | PV-1 |
| Isotype: | IgG2 |
| Immunogen: | C57BL/6N mouse T cell lymphoma EL4 cell line |
| Application: | FC |
Description
Description: CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.
Additional Text
Caution
FOR RESEARCH USE ONLY
Gene ID
12487
Gene Name
CD28
Specificity
Recognzies mouse CD28.
Uniprot ID
P31041
Purification
Purified
Antibody Clonality
Monoclonal
C2380-08J Datasheet
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