CD29 (Integrin beta 1) (MaxLight 550)
Catalogue Number: C2381-10-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3H1190 |
| Isotype: | IgG1 |
| Immunogen: | Purified human b1 integrin preparation from HT1080 fibrosarcoma cell extract. |
| Application: | IF, IP, WB, IHC, FLISA |
Description
Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. CD29 is also known as beta1 integrin or VLA-4 subunit alpha. CD29 is a ~130kD under reducing, ~115kD under non-reducing conditions single pass type I transmembrane glycoprotein. CD29 acts as the common beta subunit of the heterodimeric very late antigens 1-6, complexing with CD49a-f respectively where it forms part of the receptors for laminin, collagen and fibronectin. the VLA heterodimers mediate cell-cell and cell-matrix interactions.
Additional Text
Gene ID
3688
Gene Name
ITGB1
Uniprot ID
P05556
Specificity
3H1190 recognizes the human beta1 integrin. This antibody has been shown to bind to a ligand induced binding site antibody, binding being increased in the presence of fibronectin ligand. This antibody also enhances alpha 5-beta 1-fibronectin interactions. Species Crossreactivity: No crossreactivity with mouse or rat.
Purification
Protein G purified
Antibody Clonality
Monoclonal
C2381-10-ML550 Datasheet
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