CD31 (Platelet Endothelial Cell Adhesion Molecule, PECAM-1, EndoCAM, GPIIA', PECA1, PECAM1) (PerCP)

Catalogue Number: C2383-04P-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in 1ml saline, 0.5% BSA, 0.09% sodium azide. Labeled with PerCP.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD31\|CD31 antigen\|CD31/EndoCAM\|endoCAM\|GPIIA'\|PECA1\|PECAM-1\|platelet endothelial cell adhesion molecule\|platelet endothelial cell adhesion molecule-1
Shipping Condition:	Blue Ice
Unit(s):	100 Tests
Host name:	Mouse
Clone:	11n31
Isotype:	IgG1
Immunogen:	Activated HUVEC human umbilical vein endothelial cells
Application:	FC

Overview
Datasheets

Description

Description: The CD31 adhesion molecule, is expressed in large amounts on endothelial cells at intercellular junctions and on T cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrin avb3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

PECAM1

Gene ID

5175

Uniprot ID

P16284

Specificity

Recognizes human CD31.

Purification

Protein G purified

Antibody Clonality

Monoclonal

C2383-04P Datasheet

Price

£664.00

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