CD31 (PECAM-1, Platelet gpIIa Molecule) (MaxLight 550)
Catalogue Number: C2383-20-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Hamster |
| Clone: | 2Q682 (2H8) |
| Isotype: | IgG |
| Immunogen: | D10.G4.1 murine T cells. Epitope: Extracellular domain. |
| Application: | FC |
Description
Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. CD31 (PECAM-1, Platelet gpIIa Molecule), a ~130kD integral membrane glycoprotein, is expressed in platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney, skin biopsies from conditions such as sarcoidosis and lepromatous leprosy and bone marrow-derived hematopoietic stem cells and embryonic stem cells. CD31 mediates cell-cell adhesion. Valuable iin the study of benign and malignanat vaascular tumors. Stainiing for CD31 has also been used to measure angiogenesis, which reportedly predicts tumor recurrence.
Additional Text
Gene Name
PECAM1
Gene ID
18613
Specificity
Recognizes the 130-140kD protein, PECAM-1 found on mouse monocytes, platelets, granulocytes and endothelial cells. Effectively inhibits transmigration of activated polymorphonuclear cells and monocytes across the endothelium. In a mouse model for acute peritonis, blocks acute inflammation
Uniprot ID
Q08481
Purification
Protein A purified
Antibody Clonality
Monoclonal
C2383-20-ML550 Datasheet
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