CD31 (PECAM-1, Platelet Endothelial Cell Adhesion Molecule, PECAM-1, EndoCAM, GPIIA', PECA1, CD31, PECAM1) (FITC)

Catalogue Number: C2383-20B-FITC-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 500 ug
Host name: Rat
Clone: MEC13.3
Isotype: IgG2a, kappa
Immunogen: Polyoma middle T transformed EC line tEnd.1
Application: FC

Description

Description: CD31 is a 130-140kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1), EndoCAM, and gpIIa. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-to-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (av b3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation, and angiogenesis. This antibody has been shown to inhibit in vitro and in vivo functions of CD31.

Additional Text

Purification

Affinity Purified

Antibody Clonality

Monoclonal