CD31 (PECAM-1, Platelet gpIIa Molecule) (Azide Free) (MaxLight 650)
Catalogue Number: C2383-21-ML650-USB
| Manufacturer: | United States Biological |
| Preservative: | Azide-free |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 2Q683 (TLD-3A12) |
| Isotype: | IgG1 |
| Immunogen: | Activated, Lewis rat derived microglial cells. |
| Application: | WB, IHC, FLISA |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. CD31 (PECAM-1, Platelet gpIIa Molecule), a ~130kD integral membrane glycoprotein, is expressed in platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney, skin biopsies from conditions such as sarcoidosis and lepromatous leprosy and bone marrow-derived hematopoietic stem cells and embryonic stem cells. CD31 mediates cell-cell adhesion. Valuable iin the study of benign and malignanat vaascular tumors. Stainiing for CD31 has also been used to measure angiogenesis, which reportedly predicts tumor recurrence.
Additional Text
Gene Name
PECAM1
UniProt ID
Q3SWT0
Specificity
Recognizes rat CD31. Demonstrates a positive reaction at high dilutions against recombinant rat CD31 confirming specificity. Does not crossreact with human.
Purification
Protein G purified
Gene ID
29583
Antibody Clonality
Monoclonal
C2383-21-ML650 Datasheet
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