CD33 (gp67, Myeloid Cell Surface Antigen CD33 Precursor, Sialic Acid Binding Immunoglobulin Like Lectin 3, Siglec 3) (MaxLight 550)

Catalogue Number: C2385-01L4-ML550-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	3H1234 (WM53)
Isotype:	IgG1
Immunogen:	Human AML cells
Application:	FC, IP, WB, IHC

Overview
Datasheets

Description

Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. CD33 is a 67kD molecule expressed by monocytes, granulocyte precursors, myeloid progenitor cells and myeloid leukemias. The CD33 antigen, considered to be specific for the myeloid linage, has been reported to be present on cells of lymphoid origin. CD33 antigen is a useful marker for the diagnosis of non lymphoblastic leukemias and also for distinguishing myelogenous leukemia cells from lymphoid leukemia cells. The CD33 antigen is earlier expressed in the cytoplasm (cyCD33) than the expression on the cell membrane (mCD33) of the myeloblasts. It is more valuable using cyCD33 and cyCD13 to diagnose leukemia of AML-M0 (as the CD13 antigen is also earlier expressed in the cytoplasm (cyCD13) than the expression on the cell membrane (mCD13) of the myeloblasts). The CD33 antigen functions as an adhesion molecule.

Additional Text

Gene Name

CD33

Gene ID

945

Specificity

Recognizes human CD33 a 67kD molecule expressed by monocytes, granulocyte precursors, myeloid progenitor cells and myeloid leukemias.

Purification

Protein G purified

Uniprot ID

P20138

Antibody Clonality

Monoclonal

C2385-01L4-ML550 Datasheet

Price

£799.00

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