Catalogue Number: C2388-01R1-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rat |
| Clone: | 9E27 (MF3) |
| Isotype: | IgG2a |
| Immunogen: | IL-4 treated mouse thioglycollate-elicited peritoneal macrophages. |
| Application: | FC, IF |
Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. CD36 is an 85kD transmembrane glycoprotein which is primarily expressed on platelets, monocytes/ macrophages, smooth muscle and endothelial cells. The CD36 molecule is type B scavenger receptor, which binds to multiple ligands including thrombospondin, anionic phospholipids, oxidized low density lipoproteins and long chain fatty acids. CD36 has diverse functions and is reported to play a role in innate immunity, platelet adhesion/ aggregation and long chain fatty acid transport. The CD36 molecule also directly mediates cytoadhesion of erythrocytes infected with Plasmodium falciparum, and may be involved in the development of atherosclerotic lesions and the formation of foam cells.
12491
Q08857
CD36
Recognizes mouse CD36. Inhibits IL-4 induced thioglycollate- elicited peritoneal macrophage fusion and significantly block IL-4/GM-CSF-induced bone-marrow derived macrophage fusion.
Protein G purified
Monoclonal
CD36 (CD36 Antigen, Fatty Acid Translocase, FAT, Glycoprotein IIIb, gpIIIb, gp3b, gpIV, gp4, Leukocyte Differentiation Antigen CD36, PAS-4 Protein, PAS-IV, PASIV, Platelet Collagen Receptor, Platelet Glycoprotein 4, Platelet Glycoprotein IV, Scarb3, Thrombospondin Receptor) (MaxLight 550)