CD38 (Acute Lymphoblastic Leukemia Cells Antigen, ADP Ribosyl Cyclase, CADPr Hydrolase 1, Cyclic ADP Ribose Hydrolase, Ecto Nicotinamide Adenine Dinucleotide Glycohydrolase, I19 (Mouse), Lymphocyte Differentiation Antigen) (MaxLight 550)
Catalogue Number: C2390-01B-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3H1272 (AT13/5) |
| Isotype: | IgG1 |
| Immunogen: | CD38 |
| Application: | IP, IHC |
Description
Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. The CD38 antigen is also known as T10 antigen. The CD38 antigen is a 45kD single-chain type II glycoprotein., It is an integral membrane protein with a long extracellular C-terminal domain, a single membrane-spanning region and a short N-terminal cytoplasmic tail. The CD38 antigen is expressed on a variety of hematopoietic cells. Its distribution depends on the state of the cell differentiation and the cell activation. In adults, the CD38 molecule is expressed on earlier stage of B lymphocyte ontogeny, lost during maturation and re-expressed upon terminal differentiation to plasma cells. This molecule is also strongly expressed on thymocytes. It is found at low density on resting T lymphocytes. It is expressed on the majority of resting NK cells and monocytes. It is also found on platelets and red blood cells.
Additional Text
Specificity
Recognizes human CD38 a 45kD glycoprotein and has a reactivity pattern consistent with antibodies of the CD38 cluster. CD38 is expressed by plasma cells, monocytes, early lymphoid cells and activated T cells.
Purification
Protein A purified
Antibody Clonality
Monoclonal
C2390-01B-ML550 Datasheet
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