CD41 (CD41 Antigen, CD41b, gp2b, GPalphaIIb, GPIIb, Gta, HPA3, HPA-3, Integrin alpha IIb, Integrin alpha 2b, ITGA2B, ITGAB, Platelet Glycoprotein IIb of IIb/IIIa Complex, Platelet Fibrinogen Receptor alpha, Platelet Membrane Glycoprotein IIb, Platelet spe

Catalogue Number: C2394-02J-ML550-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 3H1299 (PM6/248)
Isotype: IgG1
Immunogen: Human platelet plasma membrane.
Application: FC

Description

Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. The CD41 cell surface antigen is a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF.

Additional Text

Uniprot ID

P08514

Gene ID

3674

Gene Name

ITGA2B

Specificity

Recognizes human CD41. Not established if this antibody recognizes free human CD41 or human CD41 only when complexed with CD61. Antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex. Species Crossreactivity: baboon, mink and mustelid.

Purification

Protein G purified

Antibody Clonality

Monoclonal

Full Name

CD41 (CD41 Antigen, CD41b, gp2b, GPalphaIIb, GPIIb, Gta, HPA3, HPA-3, Integrin alpha IIb, Integrin alpha 2b, ITGA2B, ITGAB, Platelet Glycoprotein IIb of IIb/IIIa Complex, Platelet Fibrinogen Receptor alpha, Platelet Membrane Glycoprotein IIb, Platelet specific Antigen Bak) (MaxLight 550)