CD44 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1) (PE/CY5)

Catalogue Number: C2398-69J-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide and a stabilizing agent. Labeled with PE/CY5.
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Rat
Clone:	KM201
Isotype:	IgG1, kappa
Immunogen:	Mouse bone marrow-derived stromal cells
Application:	FC, IP

Overview
Datasheets

Description

Description: CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The antibody can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte Cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells (1-6).

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

CD44

Gene ID

12505

Specificity

Recognizes all isoforms of CD44/pgp-1 (Mr 80-95kD). Reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule.

Uniprot ID

P15379

Purification

Purified

Antibody Clonality

Monoclonal

C2398-69J Datasheet

Price

£419.00

-

Quantity
Unit Size

Find out about delivery