CD45 (CD45 Antigen, B220, GP180, Leukocyte Common Antigen, LCA, L-CA, LY5, LY-5, Protein Tyrosine Phosphatase Receptor Type C, Protein Tyrosine Phosphatase Receptor Type C Polypeptide, PTPRC, T200, T200 Glycoprotein) (MaxLight 550)

Catalogue Number: C2399-03B-ML550-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD45|Lca|L-CA|leucocyte common antigen|leukocyte common antigen A|leukocyte common antigen B|protein tyrosine phosphatase, receptor-type, c polypeptide|receptor-type tyrosine-protein phosphatase C|RT7|T200|T200 glycoprotein
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: OX-1
Isotype: IgG1
Immunogen: Rat thymocyte membrane glycoproteins
Application: FC, IHC

Description

Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. The leukocyte common antigen consists of a family of heavily glycosylated membrane glycoproteins of molecular weight 180-240kD. Antibodies recognizing a common epitope on all of these isoforms are termed CD45, whilst those recognising only individual isoforms are termed CD45RA, CD45RO etc. OX-1 reacts with all forms of CD45 expressed by all haematopoietic cells, except erythrocytes. CD45 isoforms play complex roles by T-cell and B-cell antigen receptor signal transduction.

Additional Text

Gene Name

PTPRC

Uniprot ID

P04157

Specificity

Recognizes CD45, also known as the leucocyte common antigen (LCA).

Purification

Protein G purified

Gene ID

24699

Antibody Clonality

Monoclonal