CD45R (Leukocyte Common Antigen, LCA, Ly-5 T200) (PE/Cy7)
Catalogue Number: C2400-26R8-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, 0.09% sodium azide and a stabilizing agent. Labeled with PE/Cy7. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | RA3-6B2 |
| Isotype: | IgG2a, kappa |
| Immunogen: | Abelson murine leukemia virus-induced pre-B tumor cells |
| Application: | FC, IP, IHC |
Description
Description: CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.
Additional Text
Caution
FOR RESEARCH USE ONLY
Specificity
Recognizes B220 isoform of CD45, Mr 240kD.
Purification
Purified
Antibody Clonality
Monoclonal
C2400-26R8 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations