CD45RB (CD45 Antigen, B220, GP180, Leukocyte Common Antigen, LCA, L-CA, LY5, LY-5, Protein Tyrosine Phosphatase Receptor Type C Polypeptide, PTPRC, T200, T200 Glycoprotein) (MaxLight 650)

Catalogue Number: C2400-50N1-ML650-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rat
Clone: C363-16A
Isotype: IgG2a, kappa
Immunogen: Cloned mouse Th2 cell lines.
Application: IP, IHC

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. CD45 called CD45RB is a member of the protein tyrosine phosphatase (PTP) family. The PTP proteins are signalling molecules that are involved in a variety of cellular processes including cell growth, differentiation, mitosis and oncogenesis. CD45 is an essential regulator of T- and B-cell antigen receptor signalling. CD45 has various isoforms generated by different splicing of exons. Clone C363-16A recognises CD45RB, generated by exon 5 splicing. This 220kDa glycoprotein is expressed on peripheral B-cells, naive T-cells, thymocytes, macrophages and dendritic cells.

Additional Text

Gene Name

PTPRC

Gene ID

5788

Uniprot ID

P08575

Purification

Affinity Purified

Antibody Clonality

Monoclonal