CD49b (CD49b Antigen, Alpha 2 Subunit of VLA2 Receptor, Alpha 2 Subunit of VLA-2 Receptor, Collagen Receptor, GPIa, Integrin alpha 2, ITGA2, Platelet Antigen Br, Platelet Glycoprotein GPIa, Platelet Glycoprotein Ia, Platelet Membrane Glycoprotein Ia, Very

Catalogue Number: C2404-06C1-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Type:	Monoclonal Primary Antibody - Unconjugated
Shipping Condition:	Blue Ice
Unit(s):	50 ug
Host name:	Hamster
Clone:	HMa2
Isotype:	IgG
Immunogen:	Mouse colon carcinoma cell line Colon26
Application:	FC, IP, IHC

Overview
Datasheets

Description

Description: CD49b is a 150kD glycoprotein. It is a member of the integrin family, expressed on NK cells, a subset of splenic CD4+ T cells, NK-T cells, intestinal intraepithelial and lamina propria lymphocytes, epithelial cells, and platelets. By associating with CD29 (integrin b1 subunit), CD49b forms the VLA-2 (integrin a2b1) complex. It plays a critical role in both adhesion and lymphocyte activation. The primary ligands for CD49b are collagen, laminin, and fibronectin. This antibody has been shown to be useful for partially blocking CD49b mediated interactions with collagen. Additionally, this antibody blocks staining of splenic NK cells by the monoclonal antibody DX5.

Additional Text

Caution

FOR RESEARCH USE ONLY

Specificity

Recognizes mouse CD49b.

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Full Name

CD49b (CD49b Antigen, Alpha 2 Subunit of VLA2 Receptor, Alpha 2 Subunit of VLA-2 Receptor, Collagen Receptor, GPIa, Integrin alpha 2, ITGA2, Platelet Antigen Br, Platelet Glycoprotein GPIa, Platelet Glycoprotein Ia, Platelet Membrane Glycoprotein Ia, Very Late Activation Protein 2 Receptor alpha 2 Subunit, VLA2 alpha chain, VLA2, VLA-2 alpha chain, VLA-2, VLAA2)

C2404-06C1 Datasheet

Price

£264.00

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