CD49d (Antigen CD49d, CD49d Antigen, CDw49d, Alpha 4 Subunit of VLA-4 Receptor, Integrin alpha IV, Integrin alpha 4, IA4, ITGA4, LPAM23, MGC90518, Very Late Activation Protein 4 Receptor Alpha 4 Subunit, VLA4, VLA-4) (MaxLight 650)

Catalogue Number: C2404-46M2-ML650-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD49 antigen-like family member D|CD49D|integrin alpha-4|integrin alpha4B|integrin alpha-IV|Itga4B|LPAM subunit alpha|lymphocyte Peyer patch adhesion molecules subunit alpha|VLA-4 receptor, alpha 4 subunit|VLA-4 subunit alpha
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rat
Clone: 3H1501 (PS/2)
Isotype: IgG2b
Immunogen: P815 DBA/2 murine mastocytoma cells.
Application: FC, IP, IHC

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. CD49d (alpha 4 integrin), a 150kD single pass type I membrane glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively. CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1.

Additional Text

Gene Name

ITGA4

Gene ID

16401

Specificity

Recognizes mouse CD49d. Species Crossreactivity: human

Purification

Protein G purified

Uniprot ID

Q00651

Antibody Clonality

Monoclonal