CD49f (CD49f Antigen, Integrin alpha 6, ITGA6, ITGA6B, VLA 6 alpha Subunit, VLA-6) (MaxLight 650)
Catalogue Number: C2405-04V-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rat |
| Clone: | 3H1515 (NKI-GoH3) |
| Isotype: | IgG2a |
| Immunogen: | BALB/c mouse mammary tumor cells. |
| Application: | FC, IP, IHC |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. CD49f can form distinct complexes with either the CD29-antigen (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Platelet VLA-6 functions as a laminin receptor.
Additional Text
Specificity
Recognizes human CD49f. Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). Reported to inhibit platelet adhesion to laminin. Species Crossreactivity: Mouse, canine, porcine, sheep, cynomolgus monkey.
Purification
Protein G purified
Antibody Clonality
Monoclonal
C2405-04V-ML650 Datasheet
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