CD51 (CD51 Antigen, Integrin alpha V, ITGAV, Msk8, Vitronectin Receptor alpha Polypeptide, Vitronectin Receptor Subunit alpha, VNRA) (MaxLight 650)

Catalogue Number: C2405-11P-ML650-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	1110004F14Rik\|2610028E01Rik\|alpha v integrin\|CD51\|D430040G12Rik\|integrin alpha-V\|vitronectin receptor alpha polypeptide (VNRA)\|vitronectin receptor subunit alpha
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Rat
Clone:	RMV-7
Isotype:	IgG1
Immunogen:	Cultured LAK cells from Balb/c mice.
Application:	FC, IP, IHC

Overview
Datasheets

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. CD51, a 140kD alpha subunit of the vitronectin receptor, which is otherwise known as the integrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 function as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing.

Additional Text

Gene Name

ITGAV

Specificity

Recognizes mouse CD51. Reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

Purification

Protein G purified

Gene ID

16410

Uniprot ID

P43406

Antibody Clonality

Monoclonal

C2405-11P-ML650 Datasheet

Price

£832.00

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