CD79b (BCR-Ig beta)
Catalogue Number: C2431-06A-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in 100mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added. |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ug |
| Host name: | Hamster |
| Clone: | HM79-12 |
| Isotype: | IgG1 |
| Immunogen: | CD79a/CD79b heterodimers |
| Application: | FC, IP, WB |
Description
Description: Murine CD79 is a 23/21kD disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation.
Additional Text
Caution
FOR RESEARCH USE ONLY
Specificity
Recognizes the beta chain of the mouse B-cell receptor, Mr 23kD.
Purification
Purified
Antibody Clonality
Monoclonal
C2431-06A Datasheet
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