CD80 (T-lymphocyte Activation Antigen CD80, Activation B7-1 Antigen, B7, B7.1, B71, B7-1, Cd28l, Ly53, Ly-53, MIC17, TSA1)

Catalogue Number: C2432-14F-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	activation B7-1 antigen\|B7 protein\|B71\|Cd28l\|Ly53\|Ly-53\|MIC17\|T-lymphocyte activation antigen CD80\|TSA1
Shipping Condition:	Blue Ice
Unit(s):	500 ug
Host name:	Hamster
Clone:	16-10A1
Isotype:	IgG
Immunogen:	CHO cell line transfected with mouse B7
Application:	FC, IP, IHC

Overview
Datasheets

Description

Description: CD80 is a 60kD highly glycosylated protein. It is a member of the Ig superfamily, also known as B7-1, B7 and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

CD80

Gene ID

12519

Specificity

Recognizes mouse CD80. Species Crossreactivity: canine.

Uniprot ID

Q00609

Purification

Affinity Purified

Antibody Clonality

Monoclonal

C2432-14F Datasheet

Price

£439.00

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