CD81 (CD81 Antigen, 26kD Cell Surface Protein TAPA-1, Target of the Antiproliferative Antibody 1, Tapa126kD Cell Surface Protein TAPA-1, Tapa1, Tspan28)

Catalogue Number: C2433-12G-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Type:Monoclonal Primary Antibody - Unconjugated
Alias:26 kDa cell surface protein TAPA-1|CD81 antigen|Tapa1|Tapa-1|target of the antiproliferative antibody 1|Tspan28
Shipping Condition:Blue Ice
Unit(s): 50 ug, 500 ug
Host name: Hamster
Clone: Eat-2
Isotype: IgG
Immunogen: CD81+ mouse B lymphoma 38C13
Application: FC, IP, WB

Description

Description: CD81 is a 26kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1. CD81 is expressed on T and B cells, NK cells, dendritic cells, thymocytes, endothelial cells and fibroblasts. CD81 induces B cell adhesion via the VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

CD81

Gene ID

12520

Specificity

Recognizes mouse CD81. Species Crossreactivity: rat.

Purification

Affinity Purified

Uniprot ID

P35762

Antibody Clonality

Monoclonal