CD88 (CD88 Antigen, Anaphylatoxin Receptor, C5a Anaphylatoxin Chemotactic Receptor, C5aR, C5a-R, C5a Ligand, C5R1) (MaxLight 650)

Catalogue Number: C2439-61B1-ML650-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rat
Clone: 10/92
Isotype: IgG2a
Immunogen: RBL-2H3 transfected cells expressing mouse C5aR.
Application: FC, IHC

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. CD88 is a 45kD G-protein coupled cell surface receptor which is otherwise known as C5aR. The CD88 molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes.

Additional Text

Specificity

Recognizes mouse CD88. Does not block the binding of the C5a to mouse CD88.

Purification

Protein G purified

Antibody Clonality

Monoclonal