CD98 (4F2 Cell Surface Antigen Heavy Chain, 4F2 Heavy Chain Antigen, 4F2hc, 4T2HC, Antigen Defined by Monoclonal Antibody 4F2 Heavy Chain, CD98 Heavy Chain, CD98HC, Lymphocyte Activation Antigen 4F2 Large Subunit, MDU1, Monoclonal 44D7, NACAE, Solute Carr

Catalogue Number: C2443-86H1-ML650-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	4F2\|4F2 cell-surface antigen heavy chain\|4F2HC\|AI314110\|antigen identified by monoclonal antibodies 4F2\|Cd98\|CD98 antigen\|CD98 heavy chain\|Ly10\|Ly-10\|Ly-m10\|Mdu1\|Mgp-2hc\|NACAE\|solute carrier family 3 member 2\|type II transmembrane protein
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Rat
Clone:	H202-529.4.1.4
Isotype:	IgG1
Immunogen:	Thymic epithelial cells from mouse.

Overview
Datasheets

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. CD98 constitutes the heavy chain of the complex and is required for the surface expression and basolateral localization of the amino acid transporter complex in polarized epithelial cells. The CD98 heavy chain also interacts with beta 1 integrins and regulates their activation through the cytoplasmic domains and transmembrane regions. Studies suggest that overexpression of CD98 may contribute to cell growth and survival by regulating integrin signalling, and therefore may play an important role in tumorigenesis.

Additional Text

Gene Name

SLC3A2

Specificity

Recognizes mouse CD98, a type II transmembrane glycoprotein which associates with members of the L-type amino transporter family to form a heterodimeric complex..

Purification

Protein G purified

Gene ID

17254

Uniprot ID

P10852

Antibody Clonality

Monoclonal

Full Name

CD98 (4F2 Cell Surface Antigen Heavy Chain, 4F2 Heavy Chain Antigen, 4F2hc, 4T2HC, Antigen Defined by Monoclonal Antibody 4F2 Heavy Chain, CD98 Heavy Chain, CD98HC, Lymphocyte Activation Antigen 4F2 Large Subunit, MDU1, Monoclonal 44D7, NACAE, Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport) Member 2, SLC3A2) (MaxLight 650)

C2443-86H1-ML650 Datasheet

Price

£604.00

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Quantity
Unit Size

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