CD152 (CTLA-4, Cytotoxic T-lymphocyte Protein 4, Cytotoxic T-lymphocyte-associated Antigen 4, Ctla4)

Catalogue Number: C2548-83A3-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	Cd152\|CD152 antigen\|Ctla-4\|cytotoxic T-lymphocyte protein 4\|cytotoxic T-lymphocyte-associated antigen 4\|Ly-56
Shipping Condition:	Blue Ice
Unit(s):	500 ug
Host name:	Hamster
Clone:	UC10-4B9
Isotype:	IgG
Immunogen:	Mouse CTLA-4-mouse IgG2a fusion protein
Application:	ELISA, FC, IP

Overview
Datasheets

Description

Description: CD152, also known as CTLA-4 or Ly-56, is a 33kD member of the immunoglobulin superfamily. It is expressed on activated T and B lymphocytes. CD152 is similar to CD28 in aa sequence, structure, and genomic organization and these two receptors share common B7 family counter-receptors (B7-1, B7-2). Whereas CD28 delivers a costimulatory signal in T cell activation, CTLA-4 negatively regulates cell-mediated immune responses. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene ID

12477

Gene Name

CTLA4

Specificity

Recognizes mouse CD152.

Uniprot ID

P09793

Purification

Affinity Purified

Antibody Clonality

Monoclonal

C2548-83A3 Datasheet

Price

£490.00

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Quantity
Unit Size

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