CD163 (CD163 Antigen, Hemoglobin Scavenger Receptor, M130, M130 Antigen Precursor, Macrophage-associated Antigen, MM130, Scavenger Receptor Cysteine-rich Type 1 Protein M130) (MaxLight 490)
Catalogue Number: C2548-90CA-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 10B837 (2A10/11) |
| Isotype: | IgG1 |
| Immunogen: | Porcine alveolar macrophages. |
| Application: | FC, IF, IP, WB, IHC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. CD163, a 120kD cell surface glycoprotein is expressed on cells of the monocyte/macrophage lineage. The expression levels of CD163 vary during the course of macrophage differentiation. The highest levels of CD163 expression are found on tissue macrophages but bone marrow derived cells are CD163 negative. Reported to inhibit both African swine fever infection and viral particle binding to alveolar macrophages in a dose-dependent manner.
Additional Text
Gene Name
CD163
Specificity
Recognizes porcine CD163 at ~120kD in alveolar macrophage cell lysates under non-reducing conditions.
Uniprot ID
Q2VL90
Gene ID
397031
Purification
Protein A purified
Antibody Clonality
Monoclonal
C2548-90CA-ML490 Datasheet
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