CD200R1 (Cell Surface Glycoprotein CD200 Receptor 1, CD200 Cell Surface Glycoprotein Receptor, Cell Surface Glycoprotein OX2 Receptor 1, CD200R, CRTR2, MOX2R, OX2R, UNQ2522/PRO6015) (Carboxyfluorescein)
Catalogue Number: C2548-96W9-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in sodium chloride, 0.5% BSA, 0.09% sodium azide. Labeled with Carboxyfluorescein. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests |
| Host name: | Mouse |
| Clone: | 11C4 |
| Isotype: | IgG2b |
| Immunogen: | NS0-derived, recombinant human CD200 R1 (rhCD200 R1; Ala27-Leu266 (predicted): Accession # NP_620161). |
| Application: | FC |
Description
Description: CD200 R1, also known as OX-2 receptor, is one of four CD200 R-related proteins within the immunoglobulin superfamily. CD200 R1 is a type I transmembrane protein with a PTB-signaling motif in its cytoplasmic domain. Engagement of CD200 R1 by CD200 elicits an inhibitory signal in mast cells, basophils, macrophages, and dendritic cells. Alternate splicing of the human CD200 R1 mRNA generates four isoforms, two of which are truncated in the Ig-C2 domain and are likely secreted. Within the ECD, human CD200 R1 shares 56% aa sequence identity with mouse and rat CD200 R1.
Additional Text
Caution
FOR RESEARCH USE ONLY
Accession Number
NP_620161
Specificity
Recognizes human CD200 R1. Species sequence homology: mouse, rat (56%).
Purification
Protein A purified
Antibody Clonality
Monoclonal
C2548-96W9 Datasheet
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