Anti-Mouse CD8a (Ly 2.2) [2.43] - Purified
Catalogue Number: C297-LET
| Manufacturer: | Leinco Technologies, Inc |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | RT |
| Unit(s): | 50 ug, 500 ug |
| Host name: | |
| Clone: | 2.43 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IF, IP |
Description
Description: CD8 is made up of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8 is part of the Ig superfamily that expresses primarily as CD8a homodimers. CD8a is a 32-34 kD type I glycoprotein that can also form heterodimers with CD8b. CD8 is an antigen co-receptor on T cells that mediates efficient cell to cell interactions within the immune system. CD8 coupled with the T cell receptor on the T lymphocyte recognizes an antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The CD8 co-receptor also plays a role in T cell signaling by interacting with Lck (lymphocyte-specific protein tyrosine kinase) which leads to the activation of transcription factors that affect the expression of certain genes.
Additional Text
Concentration
0.5 mg/ml
Purification
Purified
Antibody Clonality
Monoclonal
Storage Note
This purified antibody is stable when stored at 2-8°C. Do not freeze.
SUPPORT
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PRODUCT
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DELIVERY
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