Chorionic Gonadotropin, Human, beta (hCGb) (PE)

Catalogue Number: C5069-06Q-PE-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. No stabilizing proteins added. Labeled with R-Phycoerythrin (PE).
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 9C79
Isotype: IgG1
Immunogen: Purified human Chorionic Gonadotropin, beta
Application: LF

Description

Description: Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the a-and b-subunits. The a-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma.

Additional Text

Accession Number

NP_000728.1

Specificity

Cross-reactivity: (tested as an antibody pair with a MAb to hCG alpha in a sandwich immunoassay to detect intact hCG) beta hCG <1%; Intact hCG 100%; LH <2%; FSH <1%; TSH <1%.

Purification

Ion Exchange

Antibody Clonality

Monoclonal