Cks2 (Cdc kinase subunit 2) (APC)
Catalogue Number: C5818-APC-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with Allophycocyanin (APC). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3G109 |
| Isotype: | IgG1 |
| Immunogen: | Synthetic peptide corresponding to the C-terminal region of human Cks2. |
| Application: | ELISA, IP, WB |
Description
Description: The Cks proteins are components of the cyclin-dependent kinase(CDK)/cyclin complexes that regulate mitosis. Thus, Cks proteins play important roles during the cell cycle1. Cks2 belongs to the highly conserved Suc1/Cks family of proteins that can bind to certain CDKs and are required for cell-cycle progression. Cks proteins may regulate the catalytic activity of the cdk2/cyclin A complex, as they have been shown to inhibit the activation of cdk2. The Cks2 gene has been localized to 9q22, which places it close to a putative tumor suppressor locus.
Additional Text
Specificity
Recognizes human Cks2. Does not crossreact with CKS1.
Purification
Protein A purified
Antibody Clonality
Monoclonal
C5818-APC Datasheet
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