Clostridium difficile Toxin A (tcdA, toxA) (MaxLight 650)

Catalogue Number: C5851-95-ML650-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 5E245
Isotype: IgG1
Immunogen: Clostridium difficile toxin A.
Application: FLISA

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Clostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.

Additional Text

Purification

Protein A purified

Antibody Clonality

Monoclonal