Anti-Human/Monkey CD40L (CD154) (Clone 5C8) - Biotin
Catalogue Number: C587-LET
| Manufacturer: | Leinco Technologies, Inc |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 25 ug |
| Host name: | |
| Clone: | 5C8 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, IP, FA |
Description
Description: CD154, also known as CD40L, gp39, TRAP, or T BAM is a 39 kDa molecule that plays a vital role in the immune system. It belongs to the tumor necrosis factor (TNF) family and is crucial for the interaction between antigen-specific lymphocytes and antigen-presenting cells1,2. By binding to CD40 it assists in the costimulation process required for activating T cells and promoting B cell proliferation. CD40L also stimulates the secretion of immunoglobulin and facilitates Ig isotype switching when it binds to CD40 on B-cells3. Moreover, CD40L regulates cytokine production by T cells4. Due to its involvement in immune responses, this molecule is of significant importance for immunological research and therapeutic interventions5,6. Clone 5C8 is a mouse monoclonal antibody produced through immunization of BALB/c mice with cells from a mouse myeloma cell line. It specifically recognizes human CD154 and binds to an epitope that differs from the CD40 binding site7,8.
Additional Text
Concentration
0.5 mg/ml
Antibody Clonality
Monoclonal
Storage Note
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
SUPPORT
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PRODUCT
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DELIVERY
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