Complement C3a Receptor (Complement Component 3a Receptor 1, Complement Component 3 Receptor 1, C3AR, C3A-R, C3AR1, AZ3B, C3a Anaphylatoxin Chemotactic Receptor, HNFAG09) (MaxLight 490)
Catalogue Number: C7850-13T1-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 10B380 (hC3aRZ1) |
| Isotype: | IgG1 |
| Immunogen: | Recombinant human Complement C3a Receptor protein |
| Application: | IHC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. The receptor for human complement component C3a (C3aR) is a 55kD cell surface protein of the rhodopsin family of G protein-coupled seven-transmembrane receptors. C3a is an anaphylatoxin, which is a potent proinflammatory mediator that possesses immunoregulatory properties. C3a regulates inflammatory functions by binding to the C3a receptor. C3aR is expressed on various tissues and leukocytes including basophils, neutrophils, mast cells, eosinophils and activated T lymphocytes. Expression levels of C3aR on human cells varies significantly between donors.
Additional Text
Gene ID
719
Gene Name
C3AR1
Uniprot ID
Q16581
Specificity
Recognizes the receptor for human complement component C3a (C3aR) at ~55kD.
Purification
Protein G purified
Antibody Clonality
Monoclonal
C7850-13T1-ML490 Datasheet
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