Complement C9 (Complement Component 9, Complement Component C9a, Complement Component C9b) (MaxLight 490)

Catalogue Number: C7850-51D-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 10B403 (002-94.8.8)
Isotype: IgG2b
Immunogen: Purified human Complement C9.
Application: FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Complement component 9 (C9) is a 71kD member of the complement C6/C7/C8/C9 family present in the blood serum and synthesized by the liver and monocytes. C9 is the last component to be added during the formation of the membrane attack complex (MAC), binding the membrane associated C5b-8 complex and resulting in the circular polymerization of 12-18 C9 molecules. This forms the hydrophilic transmembrane channel which causes cell lysis. Deficiency of C9 is associated with recurring infections by Neisseria meningitides.

Additional Text

Specificity

Recognizes human C9

Purification

Protein A purified

Antibody Clonality

Monoclonal