CXCR7 (C-X-C Chemokine Receptor Type 7, CXC-R7, CXCR-7, Chemokine Orphan Receptor 1, G-protein Coupled Receptor 159, G-protein Coupled Receptor RDC1 Homolog, RDC-1, CMKOR1, GPR159, RDC1) (Carboxyfluorescein)

Catalogue Number: C8376-25F-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in 1ml saline, 0.5% BSA, 0.09% sodium azide. Labeled with Carboxyfluorescein.
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 Tests
Host name:	Mouse
Clone:	10K17
Isotype:	IgG2a
Immunogen:	NS0 mouse myeloma cell line transfected with human CXCR7/RDC-1, Met1-Lys362 (Gly131Ser)
Application:	FC

Overview
Datasheets

Description

Description: CXCR7 can bind with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, and is also a co-receptor for several HIV and SIV strains. Reports of mRNA levels and/or protein expression indicate that CXCR7 occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendritic cells. In contrast, receptor level and ligand binding analyses indicate that surface expression of CXCR7 is restricted to tumor cells, activated endothelial cells, fetal liver cells, and a few other cell types. The basis of these inconsistent observations is not known but may be attributed to cell context and the use of different antibodies that may recognize different epitopes.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene ID

57007

Uniprot ID

P25106

Gene Name

ACKR3

Specificity

Recognizes human CXCR7.

Purification

Protein A purified

Accession Number

AAA62370

Antibody Clonality

Monoclonal

C8376-25F Datasheet

Price

£625.00

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