Cytokeratin 19 (MaxLight 490)

Catalogue Number: C9097-28C-ML490-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	40-kDa keratin intermediate filament\|CK19\|CK-19\|cytokeratin 19\|K19\|K1CS\|keratin 19, type I\|keratin, type I cytoskeletal 19\|keratin, type I, 40-kd
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	RCK108
Isotype:	IgG1, kappa
Immunogen:	Cytoskeletal preparation of T24 cells
Application:	FC, ICC, WB, IHC

Overview
Datasheets

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40kD and 68kD and isoelectric pH between 4.9-7.8. The individual cytokeratin polypeptides are designated 1 to 20. Cytokeratin 1 has the highest molecular weight and the highest isoelectric pH, while cytokeratin 19 has the lowest molecular weight and a low isoelectric pH. The cytokeratins are divided into the type I and type II subgroups, the type II family members comprising the basic to neutral cytokeratins 1-8, while the type I group comprises the acidic cytokeratins 9-20. The cytokeratins are expressed in combinations which characterize the type of epithelium. Cytokeratin 19 is the smallest human cytokeratin (40kD) and is found in many simple and invariably in some non-keratinizing stratified squamous epithelia. All adenocarcinomas tested have been positive for cytokeratin 19.

Additional Text

Gene Name

KRT19

Gene ID

3880

Uniprot ID

P08727

Specificity

Reacts with glandular epithelial cells and most carcinomas. Does not react with hepatocytes and hepatocarcinoma. Recognizes human.

Purification

Purified

Antibody Clonality

Monoclonal

C9097-28C-ML490 Datasheet

Price

£1,064.00

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Quantity
Unit Size

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