Calretinin, monoclonal
Catalogue Number: CA130-EXA
| Manufacturer: | ExAlpha |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | RT |
| Storage Condition: | 2-8°C |
| Unit(s): | 1 ml |
| Host name: | Mouse |
| Clone: | 6B3 |
| Isotype: | |
| Immunogen: | Recombinant human Calretinin 22kDa |
| Application: | IHC-P, IHC-Fr, IB |
Description
Description: The antibody is suitable for the detection of Calretinin in neurons and may be used as an aid in differential diagnosis of pleura-mesothelioma. This marker is frequently expressed in epitheloid mesothelioma, while occasionally it turns positive in sarcomatous mesothelioma and carcinoma. It was found to be negative in sarcoma (2,3) and in 90% of adenocarcinoma. Calretinin is a Calcium-binding protein related to Calmodulin and Calbindin. It is found in groups of neurons of the brain cortex, in the retina and in the spinal cord (1). More recent studies show that it is a suitable marker for mesothelioma of the lung (2, 3, 4, 5). Calretinin, no cross-reaction with Calbindin and Calmodulin.
Additional Text
Gene Name
CALB2
Gene ID
794
Uniprot ID
P22676
Antibody Clonality
Monoclonal
Storage Note
2-8°C
Application Notes
IHC(C, P), Immunoblotting
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