Biotinylated Human CEACAM-5/CD66e Protein (CAM-HM415B)
Catalogue Number: CAM-HM415B-KAT
CAM-HM415B Image
CAM-HM415B Image
CAM-HM415B Image
CAM-HM415B Image
The purity of Biotinylated Human CEACAM-5 is greater than 95% as determined by SEC-HPLC.
CAM-HM415B Image
Biotinylated Human CEACAM-5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
CAM-HM415B Image
Immobilized Biotinylated Human CEACAM-5, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CEACAM Antibody, hFc Tag with the EC50 of 10.4ng/ml determined by ELISA (QC Test).
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 74.23 kDa. Due to glycosylation, the protein migrates to 110-150 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Glycoproteins |
| Alias: | CEACAM-5; CD66e; CEA; Meconium antigen 100; Carcinoembryonic; CEACD66e; DKFZp781M2392 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.
Additional Text
Protein Tag
HIS-AviTag™
Short Description
Recombinant Biotinylated Human CEACAM-5/CD66e Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Lys35-Ala685.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Endotoxin
Less than 1 EU per µg by the LAL method.
CAM-HM415B Datasheet
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