Catalogue Number: CCR-HM02B-KAT
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The target protein has a predicted MW of 42.9kDa. |
| Physical state: | Liquid |
| Type: | Other Recombinant Protein |
| Alias: | C-C CKR-2; CCR-2; CCR2; MCP-1-R; CMKBR2; CCR2 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug |
| Application: | ELISA |
Description: The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane structures.
P41597-2
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human CCR2b VLP at 5Oeg/ml (100Oel/Well) on the plate. Dose response curve for Anti-CCR2b Antibody, hFc Tag with the EC50 of 12.0ng/ml determined by ELISA. See testing image for detail.
Less than 1 EU per µg by the LAL method.
Recombinant Human CCR2b Protein-VLP is expressed from HEK293.It contains Met1-Leu360 (It may have cross reaction with anti-His antibody).